Adrenal Insufficiency

OBJECTIVES:

  • Diagnose adrenal insufficiency
  • Differentiate between primary and secondary/tertiary adrenal insufficiency
  • Understand principles of management of adrenal insufficiency

Board set-up and Pathophysiology Review:

Primary Adrenal Insufficiency:

Secondary and tertiary adrenal insufficiency are collectively referred to as central adrenal insufficiency.

Secondary Adrenal Insufficiency:

Tertiary Adrenal Insufficiency:


Part 2: Diagnosis and Management

What are clinical signs and symptoms of adrenal insufficiency? (~ 3-5 min)

Diagnosis:

Treatment:

How do you treat adrenal crisis? (~ 3-5 min) 


TAKE HOME POINTS:


REFERENCES:

  1. Bancos, I et al. Diagnosis and management of adrenal insufficiency. Lancet Diabetes and Endocrinology. 2015; 3: 216-26.
  2. Charmandari, E, Nicolaides, NC & Chrousos, GP. Adrenal Insufficiency. Lancet. 2014; 383: 2152-67.
  3. Bastin, M, et al. Effects of Etomidate on Adrenal Suppression: A Review of Intubated Septic Patients. Hospital Pharmacy. 2014 Feb; 49(2): 177–183.